On November 2, 2017, members from Soupy for Loopy Foundation presented a check for $30,000. to Dr. Steven DuBois at Dana-Farber/Boston Children’s Cancer and Blood Disorders Center. Dr. DuBois is helping to lead a large randomized phase 3 clinical trial for children with newly diagnosed high-risk neuroblastoma at hospital sites across the United States and Canada.
According to Dr. DuBois, the primary goal of the trial is to determine whether the addition of MIBG targeted radiation therapy to standard therapy reduces the risk of relapse. MIBG therapy provides a form of targeted radiation to sites of neuroblastoma throughout the body. MIBG has been shown to be one of the most active drugs against neuroblastoma, but few tools exist to predict which patients are most likely to benefit from this approach. Another important goal of the study is to develop tools to select patients in the future who are likely to have the greatest benefit from MIBG therapy. This trial will require 5 years to enroll over 750 children with high-risk neuroblastoma.
Funds from Soupy for Loopy will be used to offset the costs associated with obtaining tumor material so that Dr. DuBois and his team can test the tumors for particular markers. These data will help future doctors decide whether a specific patient should receive MIBG therapy or not.
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